Advanced Platform Technology Center

Steve Majerus, Ph.D.

Dr. Steve Majerus received the BS, MS, and PhD degrees in Electrical Engineering from Case Western Reserve University (CWRU) in Cleveland, Ohio, USA. His primary training was in ultra-low-power application-specific integrated circuit (ASIC) design for miniaturized implantable medical devices, and he has developed ASICs for pressure sensing, neural recording, and wideband intravascular ultrasonic imaging. He has additional experience developing ASICs (in Si, SoI, and SiC) for high-temperature and aerospace applications. His doctoral thesis focused on developing and demonstrating the first cystoscopically-implanted, catheter-free bladder pressure monitor.

With the APT Center, Dr. Majerus focuses on translational research by pursuing enabling technologies and demonstrating them in appropriate preclinical or clinical settings. His work is collaborative and generally involves:

·        Custom, low-power, miniaturized, wireless circuitry

·        Flexible, polymeric substrates and encapsulation methods

·        Multiresolution signal processing and classification

·        Validation on bench phantoms, preclinical models, and with human patients

Examples of active projects:

1.       Closed-loop bladder neuromodulation using catheter-free pressure sensors (both sacral and genital nerve targets in separate studies)

2.       Wearable, non-invasive ultrasonic neuromodulation of the tibial nerve to inhibit symptoms of incontinence

3.       Wireless, catheter-free sensors for measuring bladder and bowel activity in conscious animals and humans

4.       Reduction of high blood pressure using implanted flexible pulsation sensors and autonomic neuromodulation

5.       Point-of-care monitoring for hemodialysis vascular access thrombosis risk using flexible microphone arrays and ultrasonic imaging

Curriculum Vitae

Published Work

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